Ho omisa ka leqhoa, ho tsejoang hape e le ho omisa ka leqhoa, ke mokhoa oa ho fokotsa mocheso o tlase o sebelisoang ho phekola lihlahisoa tse sa utloeng mocheso.Theknoloji hona joale ke mokhoa o tloaelehileng lik'hamphaning tse ngata tsa meriana.Hobane e omisa sehlahisoa ka bonolo ntle le ho senya ts'ebetso ea eona ea likokoana-hloko le thepa ea 'mele.
一, nalane ea mochini o omisang oa bongaka
Ka 1906, Jacques-Arsene de Assonval o ile a qapa mokhoa oa ho omisa ka leqhoa Kolecheng ea Fora e Paris.Hamorao, nakong ea Ntoa ea II ea Lefatše, e ile ea sebelisoa haholo ho boloka serum.Ho tloha ka nako eo, ho omisa ka leqhoa e se e le e 'ngoe ea mekhoa ea bohlokoa ka ho fetisisa ea ho boloka meriana e thibelang mocheso le lisebelisoa tsa likokoana-hloko.
二, melemo ea mochini o omisang oa bongaka
1, boloka lik'hemik'hale le thepa ea 'mele
Ho fapana le mekhoa ea ho omisa e thehiloeng mochesong, ho omisa ka leqhoa ho sebelisa mocheso o tlase le mokhoa o bitsoang sublimation le desorption ho etsa mouoane oa metsi.E qoba mocheso o feteletseng ho sireletsa botšepehi ba sehlahisoa, se sa ameng lik'hemik'hale kapa thepa ea 'mele.
2. Boloka tšebetso ea likokoana-hloko
Bakeng sa indasteri ea meriana, moo lihlahisoa tse ngata le mehlala e fokolang, e sa tsitsang, le e sa utloisiseng mocheso, mokhoa ona oa ho boloka o loketse.Hangata ho omisa ka leqhoa ho netefatsa ts'ebetso ea likokoana-hloko> 90%.
3, ho bonolo ho e boloka le ho e tsamaisa
Mongobo oa lithethefatsi tse omisitsoeng ke leqhoa ke <3%, e loketseng ho boloka nako e telele le ho tsamaisoa ka mocheso oa kamore.Kenya feela metsi ho khutlisetsa sehlahisoa boemong ba sona ba pele.Bokhoni ba ho tsitsisa lihlahisoa le ho eketsa sethala sa bophelo ba meriana le meriana bo entse hore ho omisa ka leqhoa e 'ngoe ea mekhoa e sebelisoang haholo indastering ea meriana.Bophelo ba lishelefo ea li-agent tse omisitsoeng ka leqhoa bo boleloa bonyane lilemo tse 5 le ho fihla ho lilemo tse 30.
三, ts'ebeliso e tloaelehileng ea mochini o omisang oa bongaka
1. Phofo ea meriana
a: Ente: motsoako o omisitsoeng ka leqhoa oa glycyrrhizin, recombinant human interferon γ, joalo-joalo.
Stem cell, biopharmaceutical, meriana ea lik'hemik'hale;
b: Liente: ente e sa sebetseng ea encephalitis, ente ea intradermal ea ente ea BCG, mumps phela ente attenuated, yellow fever phela attenuated ente, joalo-joalo.
c: Protheine: immunoglobulin, prothrombin complex ea motho, fibrinogen ea motho, serum ea chefo ea noha, serum ea chefo ea scorpion, Staphylococcus A protheine lihlahisoa tse hloekileng, joalo-joalo;
d: Lithibela-mafu: antitoxin ea diphtheria e omisitsoeng ka leqhoa, antitoxin e omisitsoeng ea tetanase, joalo-joalo;
2. Lisebelisoa tsa Meriana tsa Sechaena (ho qeta)
a: Limela: Ginseng, Notoginseng, American ginseng, Dendrobium, Scutellaria skullcap, Licorice, Radix salva, Wolfberry, safflower, honeysuckle, chrysanthemum, Ganoderma lucidum, ginger, Peony, peony, Rehmannia, yam (Huaishan, Astrachelus Cinkgo), Ginkgo Cinkgo , lekhapetla la lamunu, Tremella tremella, Hawthorn, monk fruit, Gastrodia gastrodia, Tianshan Snow Lotus, joalo-joalo;
b: Liphoofolo: jelly ea borena, placenta, cordyceps, seahorse, nyooko ea bere, noka ea likhama, mali a likhama, musk, ejiao, sodium ea heparin, joalo-joalo;
3. Lisebelisoa tse tala
Lisebelisuoa tse tala tsa likokoana-hloko, lihlahisoa tsa liphoofolo, lisebelisoa tsa lik'hemik'hale, lithethefatsi tse tsoang ka bongata;
4. Reagent ea ho lemoha
Teko ea tikoloho: li-reagents tsa tlhahlobo ea boleng ba metsi, lisebelisoa tsa tlhahlobo ea mobu le tse ling tse omisitsoeng ka leqhoa;
Reagent ea tlhahlobo ea tlhahlobo, reagent ea tlhahlobo ea tlhahlobo, reagent ea tlhahlobo ea biochemical;
5, mehlala ea likokoana-hloko, lisele tsa likokoana-hloko
Ka mohlala, etsa mefuta e sa tšoaneng ea liphoofolo le limela, ho omisa le ho boloka letlalo, cornea, lesapo, aorta, valve ea pelo le lisele tse ling tse ka thōko tsa xenogeneic kapa homologous transplantation ea liphoofolo, tse kang tse omisitsoeng ka leqhoa;
6. Likokoana-hloko le algae
Joalo ka mefuta e fapaneng ea libaktheria, tomoso, li-enzyme, protozoa, li-microalgae le tse ling tsa poloko ea nako e telele, joalo ka ho omisa.
7, lihlahisoa tsa likokoana-hloko, lithethefatsi
Joalo ka ho boloka li-antimicrobials, antitoxins, lisebelisoa tsa tlhahlobo le liente;
四, mokhoa oa ho omisa lithethefatsi
Ha e le hantle, litlhare tse omisitsoeng ka leqhoa li na le mehato e meraro ea mantlha: leqhoa, ho omisa ka lekhetlo la pele, le ho omisa ha bobeli, tse kenyeletsang:
Ho qhoqhoa: Sehlahisoa sa metsi se hoama ka potlako ho thibela ho thehoa ha likristale tse kholo tse ka senyang marako a lisele tsa thepa.
Primary drying (sublimation): Ena ke mohato oa bobeli oa mokhoa oa ho omisa ka leqhoa, moo khatello e fokotsoang le ho futhumatsa ho etsa hore metsi a leqhoa a fetohe mouoane.Ho latela mohlala, ts'ebetso ena e ka nka kae kapa kae ho tloha ho lihora tse 'maloa ho isa matsatsing a' maloa ho phethoa.Hang ha ho omisa ho felile, 93-95% ea metsi e se e felile.
Ho omisa ka bobeli (adsorption): Ena ke mohato oa ho qetela moo mocheso o ntseng o phahama ho tlosa mongobo o setseng.Metsi a setseng a qabeletsoe ka har'a matrix a tiileng a senyeha ka ho eketsa mocheso.
Joale moriana o omisitsoeng ka leqhoa o kenngoa ka har'a linkho tsa khalase tse nang le litopo tsa rabara le likatiba tse entsoeng ka aluminium.
五.Lithethefatsi tse loketseng ho omisa ka leqhoa
Mehlala ea meriana e omisitsoeng ka leqhoa ke:
ente.
antibody.
erythrocyte
plasma
hormone
libaktheria
Kokoana-hloko.
enzyme
li-probiotics
Livithamini le liminerale
Collagen peptide
electrolyte
Motsoako o sebetsang oa meriana
六, ho kgothaletswa ho omisa sehatsetsi sa meriana
Sesebelisoa sa ho omisa sehatsetsi sa liteko
Pilot freeze dryer
Sehatsetsi sa likokoana-hloko
Joaloka moetsi ea hloahloa oa litsamaiso tsa ho omisa le litharollo, "BOTHO" Instrument e na le boiphihlelo bo bongata ho R&D le tlhahiso.Se omisa sehatsetsi sa liteko, mochini o omisang sefofanelesehatsetsi sa baelojie ntlafalitsoeng ke "BOTHO" e ka fihlela litlhoko tsa lisampole tse nyane, tsa sefofane kapa tse kholo, haeba u li hloka, ka kopoiteanye le rona, re thabela ho u fa lipuisano le ho araba lipotso leha e le life tseo u nang le tsona.Sehlopha sa rona se tla thabela ho u sebeletsa.Ke labalabela ho buisana le ho sebelisana le uena! ”…
Nako ea poso: Jan-12-2024
